HOW WE HELP RESEARCHERS
Spectrum assists researchers in conducting clinical and translational research studies at Stanford University. This is accomplished through programs that support investigators at all stages of research. Benefits to researchers include:
We sponsor graduate-level award programs designed to train and advance the careers of clinical and translational researchers. We also run self-paced and expert-led training classes.
We provide funding for early-stage ideas, helping researchers develop proof-of-concept research and prototypes. These seed grants are awarded in the areas of medtech, therapeutics, diagnostics, population health sciences and community engagement.
Our staff offers free consultations on biostatistics, study design, bioethics and regulatory requirements. In addition, the Spectrum website, available 24/7, offers step-by-step guidance and resources for all stages of the clinical and translational research process.
Stanford researchers of all disciplines are able to use our new state-of-the-art facility for conducting outpatient clinical studies. In addition, our Study Navigator web portal helps research teams collaborate, track studies and book resources.
Spectrum is an independent center within Stanford University that supports health-related research activities across Stanford University.
The core mission is to accelerate the translation of basic scientific discoveries into practical solutions that improve human health, accomplished through educational programs, research support, infrastructure improvements and innovation funding.
Spectrum is funded through a Clinical and Translational Science Award (CTSA) from NIH's National Center for Advancing Translational Sciences (NCATS). As a recipient of this award, Stanford joins a national consortium of more than 60 leading biomedical institutions. Consortium institutions are working together to transform the translational science process so that new treatments and cures for disease can be delivered to patients faster.
Spectrum's New Clinical Trial Center
Stanford investigators are able to use the Jill and John Freidenrich Center for Translational Research, a state-of-the-art facility for designing and conducting human-subject studies. This center, which provides a cost-effective, friendly environment for these studies, is within walking distance of Stanford hospitals and offers on-site parking. The ground floor includes 16 patient bays with infusion chairs, four hospital beds, three pediatric study rooms, a sample-collection lab, two phlebotomy rooms and an outdoor play area with a separate entrance for pediatric subjects. There are also specialized rooms for informed-consent discussions, remote observation, sleep studies and exercise physiology testing.
THE SPECTRUM TEAM
The Spectrum organization is run by a multidisciplinary team of faculty and staff at Stanford University.
Harry B. Greenberg, MD, the Joseph D. Grant Professor of Medicine and Microbiology and Immunology, has served as the Spectrum Program Director since Spectrum’s inception in 2008. As Director, he reports directly to Ann Arvin, MD, the University's Vice Provost and Dean of Research. As the Senior Associate Dean for Research, he reports to Lloyd Minor, MD, Dean of the medical school.
Dr. Greenberg is a well-recognized experimental medicine researcher. He maintains an active research lab focused on rotavirus and influenza pathogenesis and immunity. His research interests over the past 40 years have been on important viral infections of humans, with emphasis on viral pathogenesis, immunity and vaccination. He has studied hepatitis B virus (HBV), Norwalk virus, rotavirus, hepatitis C virus (HCV), and recently, influenza virus. He was an inventor of the first effective rotavirus vaccine and spent a two-year leave of absence from Stanford in the biotechnology industry working on bringing the live, attenuated influenza vaccine (FluMist) to licensure. Dr. Greenberg is a fellow of the American Association for the Advancement of Science, a member of the American Society for Clinical Investigation, and a member of the Association of American Physicians. He is the past president of the American Society of Virology. He is a member of the IOM Drug Forum and a past member of the National Academy of Science Standing Committee on DoD Biodefense.
Spectrum Executive Committee
Philip Lavori, PhD, Chair of Health Research and Policy and a Professor of Biostatistics, is a prominent leader in the field of clinical study design. His focus over the last 20 years has been on innovations in the design of randomized clinical trials. He is one of the founders of the field of trial design for adaptive treatment strategies, and his findings have been reported in nearly 200 articles. Dr. Lavori is responsible for design, administration and assessment of biostatistics, clinical informatics, study design and bioethics components of Spectrum.
Charles Prober, MD, Senior Associate Dean for Medical Education and Professor of Pediatrics (Infectious Disease) and of Microbiology & Immunology, brings considerable translational research knowledge and accomplishments, clinical research administrative experiences, leadership skills and dedication to the mentoring and training of undergraduates, medical students, residents and clinical fellows to Spectrum. Dr. Prober’s research, published in over 150 articles, has included epidemiologic and clinical trial studies focused on pediatric infectious diseases. Dr. Prober has overall responsibility for the education and training components of the CTSA.
Branimir I. (Brandy) Sikic, MD, Professor of Medicine in the Division of Oncology, is an expert in the biology of anticancer drug resistance, the development of new cancer therapies and early phase translational trials. His current work includes studies on mechanisms of resistance to taxane drugs and genomic approaches to tumor classification. He has been published in more than 160 articles. Dr. Sikic has specific responsibility for the Clinical Research Services of Spectrum and serves to help coordinate Spectrum resources and services with those of our NIH-funded Cancer Center.
David Stevenson, MD, the Harold K. Faber Professor of Pediatrics and Chief of the Division of Neonatal and Developmental Medicine, is an established researcher in the field of neonatology. His research has led to the publication of over 450 articles. In addition to his research accomplishments, he established the California Association of Neonatology (CAN) and the California Perinatal Quality Care Collaborative (CPQCC). He served as President of the American Pediatric Society from 2005 to 2006. He is also the principal investigator of the March of Dimes Prematurity Research Center at Stanford University School of Medicine, which brings together experts from a variety of disciplines to develop new approaches toward studying and preventing preterm birth. De. Stevenson is responsible for the administration and assessment of all child health research programs in Spectrum.
Spectrum Operations Committee
David Magnus, PhD, Leader
Mildred Cho, PhD, Co-leader
Biostatistics and Study Design
Philip Lavori, PhD, Leader
David Stevenson, MD, Leader
Christy Sandborg, MD, Co-leader
Henry Lowe, MD, Leader
Clinical Research Services
Branimir I. (Brandy) Sikic, MD, Leader
David Stevenson, MD, Co-leader
Population Health Sciences and Community Engagement
Robert Harrington, MD, Leader
Marilyn Winkleby, PhD, MPH, Co-leader
Holden Maecker, PhD, Leader
Innovation & Pilots
Daria Mochly-Rosen, PhD, Leader, Therapeutics Accelerator
Paul Yock, MD, Leader, MedTech Accelerator
Atul Butte, MD, Leader, Diagnostics and Predictive Medicine Accelerator
Steven R. Alexander, MD, Leader
Research Education & Training
Steven Goodman, MD, PhD, Leader
Chris Webb, PhD, Executive Director, Administration
Martha Kessler, Executive Director, Finance
Population Health Event Draws a Crowd
More than 250 researchers and clinicians attended a colloquium to share ideas on new approaches to population-level health research.
Download agenda here.
Online "Writing in the Sciences" course
In this free online course, Kristin Sainani teaches scientists to become more effective writers, using practical examples and exercises.
Spectrum K-scholar Named Assistant Professor at UC Davis
Jonathan Riess, MD, MS, used his Spectrum KL2 award to pursue an MS in epidemiology and conduct clinical trials in thoracic malignancies. He's now an Assistant Professor in hematology and oncology at UC Davis.
Call for Innovation Seed Grant Proposals
Spectrum is reviewing research proposals for novel health-related solutions in the areas of medtech, therapeutics, diagnostics, population health and community engagement. Awards from $15K to $50K per year. Proposals are due in October.