Medical Technologies (Biodesign)
Past Pilot Grant Awards» Predictives and Diagnostics / SPADA
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Biodesign provides medical technology innovation training to teams of doctors, engineers and business students who identify a medical need, develop an invention to fill it and create a plan for bringing the technology forward into patient care.
Development of a novel monitoring system to prevent unnecessary blood product wastage
Investigator: Barrett Larson, MD, resident in anesthesiology, perioperative and pain medicine; Alex Macario, MD, MBA, professor of anesthesiology, perioperative and pain medicine; Neil Shah, MD, clinical assistant professor of pathology
Study to evaluate a new, nonhormonal treatment for vulvovaginal atrophy in cancer survivors
Investigator: Shannon MacLaughlan, MD, clinical assistant professor of obstetrics and gynecology; Doug Blayney, MD, professor of medicine
High-yield, ultrasound-guided biopsy in the peripheral lung
Investigator: Arthur Sung, MD, clinical associate professor of pulmonary and critical care medicine; Ryan Van Wert, MD, clinical instructor of medicine; Ben Cohn, graduate student in electrical engineering; Vidya Bhat, graduate student in business
Predicting clinical pregnancy with embryo mechanics after in vitro fertilization
Investigator: David Camarillo, PhD, assistant professor of bioengineering; Barry Behr, PhD, professor of obstetrics and gynecology; Livia Yanez, PhD candidate, Bioengineering
A novel device for treating chronic wound infections
Investigator: Peter Lorenz, MD, professor of plastic and reconstructive surgery; Juan Rivas-Davila, PhD, assistant professor of electrical engineering; Johan Andreasson, PhD, postdoctoral scholar in genetics; Julie Saiki, PhD candidate, chemical and systems biology; Luke Raymond, graduate student in electrical engineering; Michael Hu, MD, postdoctoral scholar in plastic and reconstructive surgery
A cost-effective solution for management of perioperative normothermia
Investigator: Peter Santa Maria, MD, instructor of otolaryngology, head and neck surgery; John Brock-Utne, clinical professor emeritus of anesthesia; Brian Kannard, Stanford MBA student; Abhinav Ramani, ex-Global Biodesign fellow
Technology licensing: http://techfinder.stanford.edu/technology_detail.php?ID=30300
Smartphone-based ophthalmic imaging system for remote triage
Investigator: Robert Chang, MD, assistant professor of ophthalmology; David Myung, MD, PhD resident, Byers Eye Institute at Stanford; Mark Blumenkranz, MD, professor and chair of ophthalmology
Journal article: http://www.journalmtm.com/2014/3d-printed-smartphone-indirect-lens-adapter-for-rapid-high-quality-retinal-imaging/
An in-situ, non-invasive method to monitor oxidative stress and gastrointestinal cancer progression
Investigator: George Fisher, MD, PhD, Colleen Haas Chair in the School of Medicine; Victor Miller, mechanical engineering PhD candidate; Mitchell Spearrin, mechanical engineering PhD candidate; Christopher Strand, mechanical engineering PhD candidate; Amato Giaccia, PhD, professor of radiation oncology; Ron Hanson, PhD, professor of mechanical engineering
Real-time visualization of beam position and dosimetry of radiation therapy
Investigator: Dominik Naczynski, PhD, radiation physics postdoctoral fellow; Cesare Jenkins, mechanical engineering MS candidate; Lei Xing, PhD, professor of radiation physics
Journal article: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265127
An intracranial access device for minimally invasive evacuation of recurrent subdural hematoma
Investigator: Stanley Hoang, MD, neurosurgery resident; Maziyar Kalani, MD, neurosurgery resident; Gordon Li, MD, assistant professor of neurosurgery
An ex-vivo gross study of radio-frequency-based denervation of pulmonary artery tissue: A translational study with implications in therapy device development for pulmonary hypertension
Investigator: Swami Gnanashanmugam, MS, MD, cardiovascular medicine postdoctoral fellow; Jeffrey Feinstein, MD, PhD, associate professor of pediatrics and cardiology
A novel device to prevent surgical wound infections: A pilot clinical study
Investigator: Mark Welton, MD, professor of surgery, and Thomas Krummel, MD, professor and chair of surgery.
Company funded: http://www.prescientsurgical.com
Hepatic neural balancing device for blood sugar control
Investigator: Paul Wang, MD, professor of cardiovascular medicine, and Jeffrey Caves, PhD, postdoctoral scholar in medicine.
A new protein microarray platform on plasmonic gold substrates
Investigator: Hongjie Dai, PhD, professor of chemistry.
High-throughput tools for insect vector-borne disease surveillance in real-world field settings
Investigator: Manu Prakash, PhD, assistant professor of bioengineering.
Development and testing of a prevention device for ventilator-associated pneumonia: The BronchoGuard
Investigator: Stephen Ruoss, MD, professor of medicine.
Screening device for neonatal jaundice in India pilot clinical study
Investigator: Vinod Bhutani, MD, professor of pediatrics, and Sandeep Sabhlok, medical student
Restoration of sight with photovoltaic retinal prosthesis, in-vivo testing of visual function
Investigator: Daniel Palanker, PhD, associate professor of ophthalmology, and Yossi Mandel, MD, PhD, postdoctoral scholar
A compact urinary catheter packaging for improved privacy, hygiene and compliance
Investigator: William Kennedy MD, associate chief of pediatric urology, and an interdisciplinary team of students from the medical, business and engineering schools.
FDA clearance: http://www.compactcath.com
A minimally invasive method of treating patients with refractory ascites, excess fluid in the space between the abdomen and abdominal organs
Investigator: Ashish Nimgaonkar, MD, biodesign fellow
Implantable tear duct stimulator
Investigators: Mark Blumenkranz, MD, professor and chair of ophthalmology, and Michael Ackerman, PhD, Biodesign fellow
In clinical trials: https://clinicaltrials.gov/ct2/results?term=oculeve&Search=Search
Development of a Novel Drug Screening Assay Using iPSC-derived Cardiomyocytes
Year: 2012 Investigators: Joseph Wu, MD, PhD, professor of cardiovascular medicine; Andrew Lee, PhD student in chemical and systems biology; Paul Yock, MD, professor of bioengineering and cardiovascular medicine
An image-guided device that prevents gallstone obstruction in patients who want to avoid surgery
Investigator: Matthew Callaghan, MD, postdoctoral scholar and former biodesign fellow, and Thomas Krummel, MD, chair of surgery.
A low-cost test for diagnosing diseases such as malaria, tuberculosis and African sleeping sickness in underserved global regions
Investigator: Manu Prakash, PhD, assistant professor of bioengineering.
Journal article: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062392
A novel approach to cardiac rhythm support that reduces complications associated with current technologies
Year: 2011 Aravind Swaminathan, MD, and Ellis Garai, both graduate students and former biodesign fellows.
An advanced system for treating atrial fibrillation, a heart rhythm problem affecting more than 2 million Americans
Investigator: Paul Wang, MD, professor of cardiovascular medicine; Fritz Prinz, PhD, chair of the mechanical engineering; Robert Robbins, MD, chair of cardiothoracic surgery; and Amin Al-Ahmad, MD, assistant professor of cardiovascular medicine.
A minimally invasive treatment for chronic venous insufficiency, in which damaged veins are not able to pump enough oxygen-poor blood back to the heart
Investigator: Fletcher Wilson, biodesign fellow and R. James Yu, MD, urology fellow.
Clearance knife: An endoscopic knife to remove Barrett's high grade dysplasia Investigators
Investigator: Tonya Kaltenbach, MD; Roy Soetikno, MD; Vijaykumar Rajasekhar, MD; and Lorenzo Deveza, MD
Stereotactic radiotherapy for renal sympathetic ablation
Investigator: Robert Chin, MD, PhD and Matt Wheeler, MD, PhD; associate professor of pediatrics
A low-cost portable electron paramagnetic resonance oximetry system for clinical applications
Investigator: Thomas Lee, ScD and Periannan Kuppusamy, PhD
Development of a prototype microfluidic detector enabling newborn screening for SCID
Investigator: Manish Butte, MD, PhD
Journal article: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313547
miRNA Rapid Diagnostic Screen
Investigator: Juan Santiago, PhD, professor of mechanical engineering
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